Article
Dexamethasone in hyperleukocytic acute myeloid leukemia.
Haematologica - 1 Jun 2018
Bertoli Sarah, Picard Muriel, Bérard Emilie, Griessinger Emmanuel, Larrue Clément, Mouchel Pierre Luc, Vergez François, Tavitian Suzanne, Yon Edwige, Ruiz Jean, Delabesse Eric, Luquet Isabelle, Linares Laetitia Karine, Saland Estelle, Carroll Martin, Danet-Desnoyers Gwenn, Sarry Audrey, Huguet Françoise, Sarry Jean Emmanuel, Récher Christian
Abstract excerpt
Patients with acute myeloid leukemia and a high white blood cell count are at increased risk of early death and relapse. Because mediators of inflammation contribute to leukostasis and chemoresistance, dexamethasone added to chemotherapy could improve outcomes. This retrospective study evaluated the impact of adding or not adding dexamethasone to chemotherapy in a cohort of 160 patients with at least 50×109 white...
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