Article
MicroRNA signatures discriminate between uterine and ovarian serous carcinomas.
Human pathology - 1 Jun 2018
Hui Pei, Gysler Stefan M, Uduman Mohamed, Togun Taiwo A, Prado Daniel E, Brambs Christine E, Nallur Sunitha, Schwartz Peter E, Rutherford Thomas J, Santin Alessandro D, Weidhaas Joanne B, Ratner Elena S
Abstract excerpt
Synchronous endometrial and ovarian malignancies occur in 5% of women presenting with endometrial cancer and 10% of patients presenting with ovarian malignancy. When a high-grade serous carcinoma concurrently involves both ovary and endometrium, pathological determination of whether they are synchronous primaries or metastatic tumors from one primary site can be challenging. MicroRNAs (miRNA) are 22-nucleotide...
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