Article
Direct-Acting Antiviral Prophylaxis in Kidney Transplantation From Hepatitis C Virus-Infected Donors to Noninfected Recipients: An Open-Label Nonrandomized Trial.
Annals of internal medicine - 17 Apr 2018
Durand Christine M, Bowring Mary G, Brown Diane M, Chattergoon Michael A, Massaccesi Guido, Bair Nichole, Wesson Russell, Reyad Ashraf, Naqvi Fizza F, Ostrander Darin, Sugarman Jeremy, Segev Dorry L, Sulkowski Mark, Desai Niraj M
Abstract excerpt
Background: Given the high mortality rate for patients with end-stage kidney disease receiving dialysis and the efficacy and safety of hepatitis C virus (HCV) treatments, discarded kidneys from HCV-infected donors may be a neglected public health resource. Objective: To determine the tolerability and feasibility of using direct-acting antivirals (DAAs) as prophylaxis before and after kidney transplantation from...
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