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Article

Acute Respiratory Distress Syndrome: Bench-to-Bedside Approaches to Improve Drug Development.

Clinical pharmacology and therapeutics - 1 Sept 2018

Hussain Musaddique, Xu Chengyun, Ahmad Mashaal, Majeed Abdul, Lu Meiping, Wu Xiling, Tang Lanfang, Wu Ximei

Abstract excerpt

Despite 50 years of extensive research, no definite drug is currently available to treat acute respiratory distress syndrome (ARDS), and the supportive therapies remain the mainstay of treatment. To improve drug development for ARDS, researchers need to deeply analyze the "omics" approaches, reevaluate the suitable therapeutic targets, resolve the problems of inadequate animal modeling, develop the strategies to...

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PMID: 29484641
DOI: 10.1002/cpt.1034
PMCID: PMC7162218

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