Article
Comprehensive virome analysis reveals the complexity and diversity of the viral spectrum in pediatric patients diagnosed with severe and mild hand-foot-and-mouth disease.
Virology - 1 May 2018
Wang Chunhua, Zhou Shuaifeng, Xue Wanhua, Shen Liang, Huang Wei, Zhang Yi, Li Xuguang, Wang Junzhi, Zhang Hong, Ma Xuejun
Abstract excerpt
The management of hand-foot-and-mouth disease(HFMD) epidemic is difficult due to the frequent emergence of non-EV71 and non-CVA16 enteroviruses and some cases testing negative for HFMD-associated causative agents. To clarify the virus spectrum of mild and severe HFMD, a comprehensive virome analysis of 238 samples was performed using next-generation sequencing (NGS). The data revealed total thirteen mammalian-...
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