Article
Direct Molecular Detection and Genotyping of Borrelia burgdorferi Sensu Lato in Cerebrospinal Fluid of Children with Lyme Neuroborreliosis.
Journal of clinical microbiology - 1 May 2018
Barstad Bjørn, Quarsten Hanne, Tveitnes Dag, Noraas Sølvi, Ask Ingvild S, Saeed Maryam, Bosse Franziskus, Vigemyr Grete, Huber Ilka, Øymar Knut
Abstract excerpt
The current diagnostic marker of Lyme neuroborreliosis (LNB), the Borrelia burgdorferisensu lato antibody index (AI) in the cerebrospinal fluid (CSF), has insufficient sensitivity in the early phase of LNB. We aimed to elucidate the diagnostic value of PCR for B. burgdorferisensu lato in CSF from children with symptoms suggestive of LNB and to explore B. burgdorferisensu lato genotypes associated with LNB in...
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