Article
The role of FTO variants in the susceptibility of polycystic ovary syndrome and in vitro fertilization outcomes in Chinese women.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Aug 2018
Liu Ai Ling, Liao Hong Qing, Zhou Jing, Nie Yu Lin, Zhou Cui Lan, Li Zhi Liang, Guo Zi Fen, He Dong Xiu, Zhu Yun Hua, Peng Cui Ying
Abstract excerpt
We investigated the association between single nucleotide polymorphisms (SNPs) in the fat mass and obesity associated (FTO) gene (rs9926289 A/G, rs79206939 A/G, rs9930506 A/G, rs8050136 A/C, and rs1588413 C/T) and polycystic ovary syndrome (PCOS), as well as outcomes of in vitro fertilization (IVF). A case-control study consisting of 147 PCOS patients and 120 healthy controls was conducted. FTO SNPs were...