Article
Familial Risks Between Urolithiasis and Cancer.
Scientific reports - 15 Feb 2018
Hemminki Kari, Hemminki Otto, Försti Asta, Sundquist Jan, Sundquist Kristina, Li Xinjun
Abstract excerpt
Urolithiasis (UL, urinary tract stone disease) has been reported to increase subsequent cancers in the urinary tract. Recently, we showed data that surveillance bias may be an important confounder in the reported associations. In the present approach we want to address the question of possible cancer risk posed by UL mechanistically. Both UL and cancer have strong genetic components and we hypothesize that...
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