Genetic diversity of equine herpesvirus 1 isolated from neurological, abortigenic and respiratory disease outbreaks.

doi:10.1111/tbed.12809

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Article

Genetic diversity of equine herpesvirus 1 isolated from neurological, abortigenic and respiratory disease outbreaks.

Transboundary and emerging diseases - 1 Jun 2018

Bryant N A, Wilkie G S, Russell C A, Compston L, Grafham D, Clissold L, McLay K, Medcalf L, Newton R, Davison A J, Elton D M

Abstract excerpt

Equine herpesvirus 1 (EHV-1) causes respiratory disease, abortion, neonatal death and neurological disease in equines and is endemic in most countries. The viral factors that influence EHV-1 disease severity are poorly understood, and this has hampered vaccine development. However, the N752D substitution in the viral DNA polymerase catalytic subunit has been shown statistically to be associated with neurological...

Topics

Abortion, Veterinary
Animals
Base Sequence
Brain Diseases
DNA, Viral
DNA-Directed DNA Polymerase
Disease Outbreaks
Equidae
Female
Genetic Variation
Herpesviridae Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Herpesvirus 1, Equid

Horse Diseases

Horses

Phylogeny

Pregnancy

Respiration Disorders

United Kingdom

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Identifiers

PMID: 29423949
DOI: 10.1111/tbed.12809
PMCID: PMC5947664

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