Article
Ion channel dysfunction in cerebellar ataxia.
Neuroscience letters - 1 Jan 2019
Bushart David D, Shakkottai Vikram G
Abstract excerpt
Cerebellar ataxias constitute a heterogeneous group of disorders that result in impaired speech, uncoordinated limb movements, and impaired balance, often ultimately resulting in wheelchair confinement. Motor dysfunction in ataxia can be attributed to dysfunction and degeneration of neurons in the cerebellum and its associated pathways. Recent work has suggested the importance of cerebellar neuronal dysfunction...
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