Article
Origin and dispersal of Hepatitis E virus.
Emerging microbes & infections - 7 Feb 2018
Forni Diego, Cagliani Rachele, Clerici Mario, Sironi Manuela
Abstract excerpt
Hepatitis E virus (HEV, genus Orthohepevirus) is a common cause of hepatitis worldwide. Human-infecting HEV strains (Orthohepevirus A) include human-restricted and enzootic genotypes. Viruses in the Orthohepevirus A species also infect rabbits (HEV-3ra), camels, and swine. Using a selection-informed method, we dated the origin of the Orthohepevirus genus at least 21 million years ago, whereas the Orthohepevirus A...
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