Article
Sofosbuvir plus ribavirin with or without peginterferon for the treatment of hepatitis C virus: Results from a phase 3b study in China.
Journal of gastroenterology and hepatology - 1 Jun 2018
Wei Lai, Xie Qing, Hou Jin Lin, Jia Jidong, Li Wu, Xu Min, Li Jun, Wu Shanming, Cheng Jun, Jiang Jianning, Wang Guiqiang, Yang Yongfeng, Mou Zhuangbo, Gao Zhi Liang, Gong Guozhong, Niu Jun Qi, Hu Peng, Tang Hong, Lin Feng, Dou Xiaoguang, Li Lanjuan, Zhang Lun Li, Nan Yuemin, Massetto Benedetta, Yang Jenny C, Knox Steven J, Kersey Kathryn, German Polina, Mo Hongmei, Jiang Deyuan, Brainard Diana M, Jiang Jiaji, Ning Qin, Duan Zhongping
Abstract excerpt
BACKGROUND AND AIM: Sofosbuvir is a nucleotide analog inhibitor of the hepatitis C virus (HCV) NS5B RNA polymerase with pangenotypic potency. This phase 3b study evaluated the safety and efficacy of sofosbuvir + ribavirin ± peginterferon in Chinese patients infected with HCV genotype 1, 2, 3, or 6. METHODS: Patients with genotype 1 or 6 received sofosbuvir + peginterferon/ribavirin for 12 weeks or...
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