Article
Integrated ovarian mRNA and miRNA transcriptome profiling characterizes the genetic basis of prolificacy traits in sheep (Ovis aries).
BMC genomics - 29 Jan 2018
Pokharel Kisun, Peippo Jaana, Honkatukia Mervi, Seppälä Arja, Rautiainen Johanna, Ghanem Nasser, Hamama Tuula-Marjatta, Crowe Mark A, Andersson Magnus, Li Meng-Hua, Kantanen Juha
Abstract excerpt
BACKGROUND: The highly prolific breeds of domestic sheep (Ovis aries) are globally valuable genetic resources for sheep industry. Genetic, nutritional and other environmental factors affect prolificacy traits in sheep. To improve our knowledge of the sheep prolificacy traits, we conducted mRNA-miRNA integrated profiling of ovarian tissues from two pure breeds with large (Finnsheep) vs. small (Texel) litter sizes...
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