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DST659 genotype of Candida albicans showing positive association between biofilm formation and dominance in Taiwan.

Medical mycology - 1 Nov 2018

Lu Jang-Jih, Lo Hsiu-Jung, Wu Yen-Mu, Chang Jia-Yuan, Chen Yin-Zhi, Wang Shao-Hung

Abstract excerpt

Based on multiple locus sequence typing, we previously found that DST659 and DST693 were dominant genotypes of Candida albicans among the bloodstream isolates at Chang-Gung Memorial Hospital at Linkou. Biofilm-forming activity, which is critical for C. albicans virulence, probably contributed to the dominance of antifungal sensitive isolates in hospital. Both in vitro membrane weighting and in vivo zebrafish egg...

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PMID: 29325080
DOI: 10.1093/mmy/myx151

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