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Article

Abnormal Complement Activation and Inflammation in the Pathogenesis of Retinopathy of Prematurity

22 Dec 2017

Abstract excerpt

Retinopathy of prematurity (ROP) is a neurovascular complication in preterm babies, leading to severe visual impairment, but the underlying mechanisms are yet unclear. The present study aimed at unravelling the molecular mechanisms underlying the pathogenesis of ROP. A comprehensive screening of candidate genes in preterms with ROP (n=189) and No-ROP (n=167) was undertaken to identify variants conferring disease...

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Identifiers

PMID: 29312345
DOI: 10.3389/fimmu.2017.01868

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