Article
IL4 (interleukin 4) induces autophagy in B cells leading to exacerbated asthma.
Autophagy - 1 Jan 2018
Xia Fucan, Deng Changwen, Jiang Yanyan, Qu Yulan, Deng Jiewen, Cai Zhijian, Ding Yuanyuan, Guo Zhenhong, Wang Jianli
Abstract excerpt
Allergic asthma is a common airway inflammatory disease in which B cells play important roles through IgE production and antigen presentation. SNP (single nucleotide polymorphism) analysis showed that Atg (autophagy-related) allele mutations are involved in asthma. It has been demonstrated that macroautophagy/autophagy is essential for B cell survival, plasma cell differentiation and immunological memory...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
