Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Next Generation Sequencing and Genome-Wide Genotyping Identify the Genetic Causes of Intellectual Disability in Ten Consanguineous Families from Jordan.

The Tohoku journal of experimental medicine - 1 Dec 2017

Froukh Tawfiq Jamal

Abstract excerpt

Intellectual disability (ID), occurs in approximately 1 to 3% of the population and tends to be higher in low-income countries and in inbred communities. Despite the high rates of consanguineous marriages and the likely enrichment for recessive forms of ID, the genetic bases of ID in Jordan are largely unstudied. In this study, whole exome sequencing (WES) and homozygosity mapping were used to identify the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human
Share to Consanguinity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to Family

Share to Genome, Human

Share to Homozygote

Share to Intellectual Disability

Share to Jordan

Source

Identifiers

PMID: 29269699
DOI: 10.1620/tjem.243.297

Genes

BSN
DHRS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Next Generation Sequencing and Genome-Wide Genotyping Identify the Genetic Causes of Intellectual Disability in Ten Consanguineous Families from Jordan.PMID 29269699Read ↗

Genetics of intellectual disability in consanguineous families.Semantic proximity Read ↗

Carrier Testing in Known Autosomal Recessive Intellectual Disability Genes in an Iranian Healthy Individual Using Exome Sequencing.Semantic proximity Read ↗

The diagnostic yield, candidate genes, and pitfalls for a genetic study of intellectual disability in 118 middle eastern families.Semantic proximity Read ↗

The Use of Next-Generation Sequencing for Research and Diagnostics for Intellectual Disability.Semantic proximity Read ↗

Genetic analysis and reporting from whole-exome sequencing data in 1052 patients with intellectual disability.Semantic proximity Read ↗

Phenotypic and genotypic characterization of families with complex intellectual disability identified pathogenic genetic variations in known and novel disease genes.Semantic proximity Read ↗

Mapping Autosomal Recessive Intellectual Disability: Combined Microarray and Exome Sequencing Identifies 26 Novel Candidate Genes in 192 Consanguineous FamiliesSemantic proximity Read ↗

Identification of pathogenic gene variants in small families with intellectually disabled siblings by exome sequencing.Semantic proximity Read ↗

Genome sequencing identifies major causes of severe intellectual disability.Semantic proximity Read ↗

Mapping autosomal recessive intellectual disability: combined microarray and exome sequencing identifies 26 novel candidate genes in 192 consanguineous families.Semantic proximity Read ↗

Unique Variant Spectrum in a Jordanian Cohort with Inherited Retinal Dystrophies.Semantic proximity Read ↗

Whole-exome sequencing identified five novel de novo variants in patients with unexplained intellectual disability.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.