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Article

A 12.3-kb Duplication Within the VWF Gene in Pigs Affected by Von Willebrand Disease Type 3.

G3 (Bethesda, Md.) - 2 Feb 2018

Lehner Stefanie, Ekhlasi-Hundrieser Mahnaz, Detering Carsten, Allerkamp Hanna, Pfarrer Christiane, von Depka Prondzinski Mario

Abstract excerpt

Von Willebrand Disease (VWD) type 3 is a serious and sometimes fatal hereditary bleeding disorder. In pigs, the disease has been known for decades, and affected animals are used as models for the human disease. Due to the recessive mode of inheritance of VWD type 3, severe bleeding is typically seen in homozygous individuals. We sequenced the complete porcine VWF (Von Willebrand Factor) complementary DNA (cDNA)...

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Identifiers

PMID: 29208651
DOI: 10.1534/g3.117.300432
PMCID: PMC5919753

Genes

VWF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A 12.3-kb Duplication Within the VWF Gene in Pigs Affected by Von Willebrand Disease Type 3.PMID 29208651Read ↗

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