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Article

P4HB and PDIA3 are associated with tumor progression and therapeutic outcome of diffuse gliomas.

Oncology reports - 1 Feb 2018

Zou Hecun, Wen Chunjie, Peng Zhigang, Shao Ying-Υing, Hu Lei, Li Shuang, Li Cuilin, Zhou Hong-Hao

Abstract excerpt

Diffuse gliomas are the most common type of primary brain and central nervous system (CNS) tumors. Protein disulfide isomerases (PDIs) such as P4HB and PDIA3 act as molecular chaperones for reconstructing misfolded proteins, and are involved in endoplasmic reticulum stress and the unfolded protein response. The present study focused on the role of P4HB and PDIA3 in diffuse gliomas. Analysis of GEO and HPA data...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29207176
DOI: 10.3892/or.2017.6134
PMCID: PMC5783617

Genes

PDIA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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