Article
Best practices for authenticating cell lines.
In vitro cellular & developmental biology. Animal - 1 Dec 2017
Nims Raymond W, Reid Yvonne
Abstract excerpt
Experiments using cell cultures are only valid to the extent that the cell culture is a true model system for the biological system being investigated. To assure that a cell line is and remains an appropriate biological model, its identity, purity, ploidy, and phenotype must be maintained. These characteristics comprise and determine the authenticity of a cell line. Routine monitoring of the cell line through...
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