Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Post-LASIK exacerbation of granular corneal dystrophy type 2 in members of a chinese family.

Eye (London, England) - 1 Jan 2018

Chao-Shern C, Me R, DeDionisio L A, Ke B L, Nesbit M A, Marshall J, Moore C B T

Abstract excerpt

PurposeThe post-LASIK exacerbation of corneal dystrophy, otherwise asymptomatic, is almost exclusively associated with the TGFBI gene mutations at codon 124 in exon 4 and codon 555 in exon 12. It is our intention to demonstrate that the pre-operative genetic screening for TGFBI mutations should be mandatory for refractive surgery candidates.Patients and MethodsIn this study, we reviewed the proband's post-LASIK...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cornea
Share to Corneal Dystrophies, Hereditary
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Extracellular Matrix Proteins

Share to Genetic Testing

Share to Pedigree

Share to Polymerase Chain Reaction

Share to Transforming Growth Factor beta

Source

Open in PubMed Open full text

Identifiers

PMID: 29192679
DOI: 10.1038/eye.2017.265
PMCID: PMC5770725

Genes

TGFBI

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Post-LASIK exacerbation of granular corneal dystrophy type 2 in members of a chinese family.PMID 29192679Read ↗

TGFBI Gene Mutation Analysis of Clinically Diagnosed Granular Corneal Dystrophy Patients Prior to PTK: A Pilot Study from Eastern China.Semantic proximity Read ↗

TGFBI gene mutations in a Korean population with corneal dystrophy.Semantic proximity Read ↗

Phenotype-genotype correlations in patients with TGFBI-linked corneal dystrophies in Taiwan.Semantic proximity Read ↗

Genetic and phenotypic investigation of a Chinese pedigree with lattice corneal dystrophy IIIB subtype.Semantic proximity Read ↗

Compound Heterozygous Mutations in TGFBI Cause a Severe Phenotype of Granular Corneal Dystrophy Type 2Semantic proximity Read ↗

An R124C mutation in TGFBI caused lattice corneal dystrophy type I with a variable phenotype in three Chinese families.Semantic proximity Read ↗

[Analysis of TGFBI gene mutation in a Chinese pedigree affected with lattice corneal dystrophy].Semantic proximity Read ↗

Prevalence of granular corneal dystrophy type 2-related TGFBI p.R124H variant in a South Korean population.Semantic proximity Read ↗

TGFBI gene mutations analysis in Chinese families with corneal dystrophies.Semantic proximity Read ↗

Molecular genetics of Chinese families with TGFBI corneal dystrophies.Semantic proximity Read ↗

Anticipation in familial lattice corneal dystrophy type I with R124C mutation in the TGFBI (BIGH3) gene.Semantic proximity Read ↗

[Analyses of TGFBI gene mutation spectrum in four Chinese families with corneal dystrophy].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.