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Article

Somatic PTPN11 Mutation in a Child With Neuroblastoma and Protein Losing Enteropathy.

Journal of pediatric hematology/oncology - 1 May 2018

Obasaju Patience, Brondon Jennifer, Mir Sabina, Fordham Lynn A, Lee Sang, Blatt Julie

Abstract excerpt

Neuroblastoma and protein losing enteropathy (PLE) are diagnoses commonly seen by oncologists and gastroenterologists, respectively. The concurrence of these 2 entities is rare, and not well explained. We describe the sixth case of PLE in a child with neuroblastoma, and the first for which genetic information is available. Tumor DNA had a mutation in the PTPN11 gene, which has been described in neuroblastoma, and...

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Source

Identifiers

PMID: 29189514
DOI: 10.1097/MPH.0000000000000903

Genes

PTPN11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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