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Similarities between acylcarnitine profiles in large for gestational age newborns and obesity

20 Nov 2017

Abstract excerpt

Large for gestational age (LGA) newborns have an increased risk of obesity, insulin resistance, and metabolic syndrome. Acylcarnitine profiles in obese children and adults are characterized by increased levels of C3, C5, and certain medium-chain (C12) and long-chain (C14:1 and C16) acylcarnitines. C2 is also increased in insulin-resistant states. In this 1-year observational study of 2514 newborns (246 LGA...

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PMID: 29176728
DOI: 10.1038/s41598-017-15809-4

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