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Article

Differential use of danger and safety signals in an animal model of anxiety vulnerability: The behavioral economics of avoidance.

Progress in neuro-psychopharmacology & biological psychiatry - 2 Mar 2018

Spiegler Kevin M, Fortress Ashley M, Pang Kevin C H

Abstract excerpt

Differential processing of danger and safety signals may underlie symptoms of anxiety disorders and posttraumatic stress disorder. One symptom common to these disorders is pathological avoidance. The present study examined whether danger and safety signals influence avoidance differently in anxiety-vulnerable Wistar-Kyoto (WKY) rats and Sprague Dawley (SD) rats. SD and WKY rats were tested in a novel progressive...

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Identifiers

PMID: 29175308
DOI: 10.1016/j.pnpbp.2017.11.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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