Article
Haplotype analysis of the germacrene A synthase gene and association with cynaropicrin content and biological activities in Cynara cardunculus.
Molecular genetics and genomics : MGG - 1 Apr 2018
Ferro Ana Margarida, Ramos Patrícia, Guerra Ângela, Parreira Paula, Brás Teresa, Guerreiro Olinda, Jerónimo Eliana, Capel Carmen, Capel Juan, Yuste-Lisbona Fernando J, Duarte Maria F, Lozano Rafael, Oliveira M Margarida, Gonçalves Sónia
Abstract excerpt
Cynara cardunculus: L. represents a natural source of terpenic compounds, with the predominant molecule being cynaropicrin. Cynaropicrin is gaining interest since it has been correlated to anti-hyperlipidaemia, antispasmodic and cytotoxicity activity against leukocyte cancer cells. The objective of this work was to screen a collection of C. cardunculus, from different origins, for new allelic variants in...
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