Article
Precision medicine for urothelial bladder cancer: update on tumour genomics and immunotherapy.
Nature reviews. Urology - 1 Feb 2018
Felsenstein Kenneth M, Theodorescu Dan
Abstract excerpt
Effective management of advanced urothelial bladder cancer is challenging. New discoveries that improve our understanding of molecular bladder cancer subtypes have revealed numerous potentially targetable genomic alterations and demonstrated the efficacy of treatments that harness the immune system. These findings have begun to change paradigms of bladder cancer therapy. For example, DNA repair pathway mutations...
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