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Article

Using prognostic models in CLL to personalize approach to clinical care: Are we there yet?

Blood reviews - 1 Mar 2018

Mina Alain, Sandoval Sus Jose, Sleiman Elsa, Pinilla-Ibarz Javier, Awan Farrukh T, Kharfan-Dabaja Mohamed A

Abstract excerpt

Four decades ago, two staging systems were developed to help stratify CLL into different prognostic categories. These systems, the Rai and the Binet staging, depended entirely on abnormal exam findings and evidence of anemia and thrombocytopenia. Better understanding of biologic, genetic, and molecular characteristics of CLL have contributed to better appreciating its clinical heterogeneity. New prognostic...

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Identifiers

PMID: 29122300
DOI: 10.1016/j.blre.2017.10.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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