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Aspergillus fumigatusadhesion factors in dormant conidia revealed through comparative phenotypic and transcriptomic analyses

8 Nov 2017

Abstract excerpt

Aspergillus fumigatus is an important fungal pathogen of humans. Inhaled conidia of A. fumigatus adhere to pulmonary epithelial cells, causing opportunistic infection. However, little is known about the molecular mechanism of the adherence of resting conidia. Fungal molecules adhesive to host cells are presumed to be displayed on the conidial surface during conidial formation as a result of changes in gene...

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PMID: 29113011
DOI: 10.1111/cmi.12802

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