Article
Temporal association of rotavirus vaccination and genotype circulation in South Africa: Observations from 2002 to 2014.
Vaccine - 12 Nov 2018
Page N A, Seheri L M, Groome M J, Moyes J, Walaza S, Mphahlele J, Kahn K, Kapongo C N, Zar H J, Tempia S, Cohen C, Madhi S A
Abstract excerpt
BACKGROUND: Rotavirus vaccination has reduced diarrhoeal morbidity and mortality globally. The monovalent rotavirus vaccine was introduced into the public immunization program in South Africa (SA) in 2009 and led to approximately 50% reduction in rotavirus hospitalization in young children. The aim of this study was to investigate the rotavirus genotype distribution in SA before and after vaccine introduction....
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