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Article

β-1,3-glucanase disrupts biofilm formation and increases antifungal susceptibility of Candida albicans DAY185.

International journal of biological macromolecules - 1 Mar 2018

Tan Yulong, Ma Su, Leonhard Matthias, Moser Doris, Schneider-Stickler Berit

Abstract excerpt

β-1,3-glucan plays a role in Candida biofilm formation and survival of biofilm-forming Candida to stresses. In this study, we evaluated the antibiofilm activity of β-1,3-glucanase, which can degrade poly-β(1→3)-glucose of Candida albicans biofilms. Biofilm was dispersed by 55.96%. β-1,3-glucanase had no effect on Candida planktonic growth as well as adhesion. β-1,3-glucanase markedly enhanced the antifungal...

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Identifiers

PMID: 29104052
DOI: 10.1016/j.ijbiomac.2017.11.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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