Article
Novel Muscle-Specific Genes TCAP, TNNI1, and FHL1 in Cattle: SNVs, Linkage Disequilibrium, Combined Genotypes, Association Analysis of Growth Performance, and Carcass Quality Traits and Expression Studies.
Animal biotechnology - 1 Jan 2018
He Hua, Hu Zhi-Gang, Tserennadmid Sodnompil, Chen Si, Liu Xiao-Lin
Abstract excerpt
TCAP, TNNI1, and FHL1 regulate muscle growth and development. In this study, four single nucleotide variants (SNVs) were discovered in almost all of the exon and intron regions of the TCAP, TNNI1, and FHL1 genes using DNA pooled sequencing, polymerase chain reaction (PCR)-RFLP, and forced-PCR-RFLP methods in 576 cattle. Four SNVs were significantly associated with the growth performance and carcass quality traits...
Topics
- Animals
- Cattle
- Exons
- Genetic Association Studies
- Genetic Markers
- Genetic Variation
- Genetics, Population
- Genotype
- Haplotypes
- Introns
- Linkage Disequilibrium