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Novel insights into the pathways regulating the canine hair cycle and their deregulation in alopecia X

24 Oct 2017

Abstract excerpt

Alopecia X is a hair cycle arrest disorder in Pomeranians. Histologically, kenogen and telogen hair follicles predominate, whereas anagen follicles are sparse. The induction of anagen relies on the activation of hair follicle stem cells and their subsequent proliferation and differentiation. Stem cell function depends on finely tuned interactions of signaling molecules and transcription factors, which are not...

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PMID: 29065140
DOI: 10.1371/journal.pone.0186469

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