Article
In utero negativization of Zika virus in a foetus with serious central nervous system abnormalities.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases - 1 May 2018
Rodó C, Suy A, Sulleiro E, Soriano-Arandes A, Antón A, García-Ruiz I, Arévalo S, Vázquez É, Vázquez A, de Ory F, Sánchez-Seco M P, Rodrigo C, Pumarola T, Carreras E
Abstract excerpt
We describe a case of a pregnant woman with Zika virus (ZIKV) infection and a foetus with severe brain malformations. ZIKV tested positive in amniotic fluid at 19 weeks but was negative at delivery. The newborn did not meet the case definition of congenital ZIKV syndrome because neither ZIKV RNA nor IgM antibodies were detected; however, prenatal brain lesions were confirmed after birth (Graphical Abstract).
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