Article
Emergence of Various NDM-Type-Metallo-β-Lactamase-Producing Escherichia coli Clinical Isolates in Nepal.
Antimicrobial agents and chemotherapy - 1 Dec 2017
Shrestha Basudha, Tada Tatsuya, Shimada Kayo, Shrestha Shovita, Ohara Hiroshi, Pokhrel Bharat Mani, Sherchand Jeevan B, Kirikae Teruo
Abstract excerpt
Of 250 clinical isolates of Escherichia coli obtained in Nepal, 38 were carbapenem resistant, with MICs of imipenem or meropenem of ≥4 μg/ml. All 38 isolates harbored the following blaNDMs: blaNDM-1, blaNDM-3, blaNDM-4, blaNDM-5, blaNDM-7, blaNDM-12, and blaNDM-13 Most of these isolates also harbored the 16S rRNA methylase gene(s) armA, rmtB, and/or rmtC.
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