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Article

Driving mosquito refractoriness to Plasmodium falciparum with engineered symbiotic bacteria

28 Sept 2017

Abstract excerpt

Getting to the guts of mosquito control Malaria persistently evades our best efforts to eliminate it. Pike et al. genetically modified malaria vector mosquitoes to be more immune-resistant to infection by the parasite, which altered the composition of the mosquitoes' gut bacteria. Genetically modified male (female) mosquitoes preferentially mated with wild-type females (males). Ten generations later, the...

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Share to Insect symbiosis and bacterial influences
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PMID: 28963255
DOI: 10.1126/science.aan5478

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