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Microbiota regulates bone marrow mesenchymal stem cell lineage differentiation and immunomodulation

29 Sept 2017

Abstract excerpt

Health is dependent on the homeostasis of both inner and external microenvironments. The microbiota as the external microenvironment plays a critical role in regulation of several organ systems in mammals. However, it is unclear whether the microbiota regulates homeostasis of the skeletal system and bone marrow mesenchymal stem cells (BMMSCs). Here, using a well-established germ-free (GF) mouse model, we show...

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PMID: 28962644
DOI: 10.1186/s13287-017-0670-7

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