Article
Autochthonous Transmission of East/Central/South African Genotype Chikungunya Virus, Brazil.
Emerging infectious diseases - 1 Oct 2017
Cunha Marcela S, Cruz Nádia V G, Schnellrath Laila C, Medaglia Maria Luiza Gomes, Casotto Michele E, Albano Rodolpho M, Costa Luciana J, Damaso Clarissa R
Abstract excerpt
We isolated East/Central/South African genotype chikungunya virus during the 2016 epidemic in Rio de Janeiro, Brazil. Genome sequencing revealed unique mutations in the nonstructural protein 4 (NSP4-A481D) and envelope protein 1 (E1-K211T). Moreover, all Brazil East/Central/South isolates shared the exclusive mutations E1-M407L and E2-A103T.
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