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Systematic Mutagenesis of Serine Hydroxymethyltransferase Reveals an Essential Role in Nematode Resistance.

Plant physiology - 1 Nov 2017

Kandoth Pramod K, Liu Shiming, Prenger Elizabeth, Ludwig Andrew, Lakhssassi Naoufal, Heinz Robert, Zhou Zhou, Howland Amanda, Gunther Joshua, Eidson Samantha, Dhroso Andi, LaFayette Peter, Tucker Donna, Johnson Sarah, Anderson James, Alaswad Alaa, Cianzio Silvia R, Parrott Wayne A, Korkin Dmitry, Meksem Khalid, Mitchum Melissa G

Abstract excerpt

Rhg4 is a major genetic locus that contributes to soybean cyst nematode (SCN) resistance in the Peking-type resistance of soybean (Glycine max), which also requires the rhg1 gene. By map-based cloning and functional genomic approaches, we previously showed that the Rhg4 gene encodes a predicted cytosolic serine hydroxymethyltransferase (GmSHMT08); however, the novel gain of function of GmSHMT08 in SCN resistance...

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Identifiers

PMID: 28912378
DOI: 10.1104/pp.17.00553
PMCID: PMC5664460

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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