Article
In utero development of memory T cells.
Seminars in immunopathology - 1 Nov 2017
Zhivaki Dania, Lo-Man Richard
Abstract excerpt
Pathogen-specific immune memory develops subsequent to primary exposure to antigen, mainly in the context of infection or vaccination to provide protection. Although a safe fetal life requires a tolerogenic environment in order to circumvent unnecessary inflammatory responses, it needs to be prepared in utero to face the microbial environment outside the womb. The possibility of immune memory generation in the...
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