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Differentiation and Application of Induced Pluripotent Stem Cell-Derived Vascular Smooth Muscle Cells.

Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2017

Maguire Eithne Margaret, Xiao Qingzhong, Xu Qingbo

Abstract excerpt

Vascular smooth muscle cells (VSMCs) play a role in the development of vascular disease, for example, neointimal formation, arterial aneurysm, and Marfan syndrome caused by genetic mutations in VSMCs, but little is known about the mechanisms of the disease process. Advances in induced pluripotent stem cell technology have now made it possible to derive VSMCs from several different somatic cells using a selection...

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Aneurysm
Marfan Syndrome
Muscle Development
Myocytes, Smooth Muscle
Neointima

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Regenerative Medicine

Stem Cell Transplantation

Tissue Engineering

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PMID: 28860223
DOI: 10.1161/ATVBAHA.117.309196

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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