Dendritic transport of tick-borne flavivirus RNA by neuronal granules affects development of neurological disease

Abstract excerpt

Significance Flaviviruses represent a significant threat to public health worldwide, and several cause severe neurological disease in humans and animals. However, no specific treatment has been developed, due to the lack of information about their detailed pathogenic mechanisms. In the current study, we reveal that the transport of viral RNA of tick-borne flavivirus in neuronal dendrites is involved in the...

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