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Stem cell manipulation, gene therapy and the risk of cancer stem cell emergence

25 Jul 2017

Abstract excerpt

Stem cells (SCs) have been extensively studied in the context of regenerative medicine. Human hematopoietic stem cell (HSC)-based therapies have been applied to treat leukemic patients for decades. Handling of mesenchymal stem cells (MSCs) has also raised hopes and concerns in the field of tissue engineering. Lately, discovery of cell reprogramming by Yamanaka's team has profoundly modified research strategies...

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PMID: 28815178
DOI: 10.21037/sci.2017.07.03

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