Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Implications of the FMR1 Premutation for Children, Adolescents, Adults, and Their Families.

Pediatrics - 1 Jun 2017

Wheeler Anne, Raspa Melissa, Hagerman Randi, Mailick Marsha, Riley Catharine

Abstract excerpt

BACKGROUND AND OBJECTIVES: Given the nature of FMR1 gene expansions, most biological mothers, and often multiple other family members of children with fragile X syndrome (FXS), will have a premutation, which may increase individual and family vulnerabilities. This article summarizes important gaps in knowledge and notes potential implications for pediatric providers with regard to developmental and medical risks...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ataxia
Share to Autism Spectrum Disorder
Share to DNA Repeat Expansion

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Executive Function

Share to Fragile X Syndrome

Share to Primary Ovarian Insufficiency

Share to Tremor

Share to Trinucleotide Repeats

Source

Open in PubMed Open full text

Identifiers

PMID: 28814538
DOI: 10.1542/peds.2016-1159D
PMCID: PMC5621635

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Implications of the FMR1 Premutation for Children, Adolescents, Adults, and Their Families.PMID 28814538Read ↗

Family as a Context for Child Development: Mothers with the FMR1 Premutation and Their Children with Fragile X Syndrome.Semantic proximity Read ↗

Broad clinical involvement in a family affected by the fragile X premutation.Semantic proximity Read ↗

Genetic counseling and testing for FMR1 gene mutations: practice guidelines of the national society of genetic counselors.Semantic proximity Read ↗

FMR1 and the fragile X syndrome: human genome epidemiology review.Semantic proximity Read ↗

A review of fragile X premutation disorders: expanding the psychiatric perspective.Semantic proximity Read ↗

[FMR1 PREMUTATION CARRIERS - ARE THEY REALLY ASYMPTOMATIC?]Semantic proximity Read ↗

Health problems in females carriers of premutation in the FMR1 gene.Semantic proximity Read ↗

Autism spectrum disorder in the fragile X premutation state: possible mechanisms and implications.Semantic proximity Read ↗

Insight and Recommendations for Fragile X-Premutation-Associated Conditions from the Fifth International Conference on FMR1 Premutation.Semantic proximity Read ↗

A Comprehensive Review of Fragile X Syndrome and Fragile X Premutation Associated Conditions in AfricaSemantic proximity Read ↗

The Fragile X premutation: new insights and clinical consequences.Semantic proximity Read ↗

A Comprehensive Review of Fragile X Syndrome and Fragile X Premutation Associated Conditions in Africa.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.