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Article

Exosomes from embryonic mesenchymal stem cells alleviate osteoarthritis through balancing synthesis and degradation of cartilage extracellular matrix.

Stem cell research & therapy - 14 Aug 2017

Wang Yafei, Yu Dongsheng, Liu Zhiming, Zhou Fang, Dai Jun, Wu Bingbing, Zhou Jing, Heng Boon Chin, Zou Xiao Hui, Ouyang Hongwei, Liu Hua

Abstract excerpt

BACKGROUND: Mesenchymal stem cell therapy for osteoarthritis (OA) has been widely investigated, but the mechanisms are still unclear. Exosomes that serve as carriers of genetic information have been implicated in many diseases and are known to participate in many physiological processes. Here, we investigate the therapeutic potential of exosomes from human embryonic stem cell-induced mesenchymal stem cells...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28807034
DOI: 10.1186/s13287-017-0632-0
PMCID: PMC5556343

Genes

ADAMTS5
MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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