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Article

Self-organization process in newborn skin organoid formation inspires strategy to restore hair regeneration of adult cells

10 Aug 2017

Abstract excerpt

Significance This study opens avenues to improve the ability of adult skin cells to form a fully functional skin, with clinical applications. Our investigation elucidates a relay of molecular events and biophysical processes at the core of the self-organization process during tissue morphogenesis. Molecules key to the multistage morphological transition are identified and can be added or inhibited to restore the...

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PMID: 28798065
DOI: 10.1073/pnas.1700475114

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