Article
Phenotypic heterogeneity of peripheral monocytes in healthy dogs.
Veterinary immunology and immunopathology - 1 Aug 2017
Gibbons Natalie, Goulart Michelle R, Chang Yu-Mei, Efstathiou Konstantinos, Purcell Robert, Wu Ying, Peters Laureen M, Turmaine Mark, Szladovits Balazs, Garden Oliver A
Abstract excerpt
Monocytes are key cells of the innate immune system. Their phenotypic and functional roles have been investigated in humans, mice and other animals, such as the rat, pig and cow. To date, detailed phenotypic analysis of monocytes has not been undertaken in dogs. Two important surface markers in human monocytes are CD14 and MHC class II (MHC II). By flow cytometry, we demonstrated that canine monocytes can be...
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