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Article

Embryo implantation evolved from an ancestral inflammatory attachment reaction

26 Jul 2017

Abstract excerpt

) as a model. Transcriptomic analysis shows that term pregnancy in the opossum is characterized by an inflammatory response consistent with implantation in humans and mice. This immune response is temporally correlated with the loss of the eggshell, and we used immunohistochemistry to report that this reaction occurs at the materno-fetal interface. We demonstrate that key markers of implantation, including...

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PMID: 28747528
DOI: 10.1073/pnas.1701129114

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