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Derivative Technology of DNA Barcoding (Nucleotide Signature and SNP Double Peak Methods) Detects Adulterants and Substitution in Chinese Patent Medicines.

Scientific reports - 19 Jul 2017

Gao Zitong, Liu Yang, Wang Xiaoyue, Song Jingyuan, Chen Shilin, Ragupathy Subramanyam, Han Jianping, Newmaster Steven G

Abstract excerpt

Lonicerae japonicae Flos has been used to produce hundred kinds of Chinese patent medicines (CPMs) in China. Economically motivated adulterants have been documented, leading to market instability and a decline in consumer confidence. ITS2 has been used to identify raw medicinal materials, but it's not suitable for the identification of botanical extracts and complex CPMs. Therefore, a short barcode for the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28724933
DOI: 10.1038/s41598-017-05892-y
PMCID: PMC5517575

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