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Article

The lncRNA NEAT1 facilitates cell growth and invasion via the miR-211/HMGA2 axis in breast cancer.

International journal of biological macromolecules - 1 Dec 2017

Li Xuerui, Wang Shuxia, Li Zhenzhong, Long Xiaoyu, Guo Zibai, Zhang Guochun, Zu Jian, Chen Yu, Wen Linzhu

Abstract excerpt

Long non-coding RNAs play a significant role in cancer metastasis. Studies have demonstrated that LncRNA NEAT1 promotes cancer progression. We aimed to explore whether NEAT1 regulated growth and invasion in breast cancer cells. We provided evidence that lncRNA NEAT1 was up-regulated in breast cancer cell lines and tissues. NEAT1 promoted invasion through inducing Epithelial-mesenchymal transition (EMT) and NEAT1...

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Share to Epithelial-Mesenchymal Transition
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28720546
DOI: 10.1016/j.ijbiomac.2017.07.053

Genes

HMGA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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