Article
System-wide organization of actin cytoskeleton determines organelle transport in hypocotyl plant cells.
Proceedings of the National Academy of Sciences of the United States of America - 11 Jul 2017
Breuer David, Nowak Jacqueline, Ivakov Alexander, Somssich Marc, Persson Staffan, Nikoloski Zoran
Abstract excerpt
The actin cytoskeleton is an essential intracellular filamentous structure that underpins cellular transport and cytoplasmic streaming in plant cells. However, the system-level properties of actin-based cellular trafficking remain tenuous, largely due to the inability to quantify key features of the actin cytoskeleton. Here, we developed an automated image-based, network-driven framework to accurately segment and...
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